141947-00-4

Basic information

• Product Name: Benzene, [1-methoxy-1-(trifluoromethyl)-2-propynyl]-, (R)-
• CAS NO: 141947-00-4
• Molecular Formula: C11H9F3O
• Molecular Weight: 214.187
• Mol File: 141947-00-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, [1-methoxy-1-(trifluoromethyl)-2-propynyl]-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [1-methoxy-1-(trifluoromethyl)-2-propynyl]-, (R)-(141947-00-4)
• EPA Substance Registry System: Benzene, [1-methoxy-1-(trifluoromethyl)-2-propynyl]-, (R)-(141947-00-4)

Safety Data

• Hazardous Substances Data: 141947-00-4(Hazardous Substances Data)

Upstream product

• 88445-11-8 (S)-4,4,4-trifluoro-3-phenyl-3-hydroxybutyne 
• 74-88-4 methyl iodide 

Downstream Products

• 17257-71-5 (S)-Mosher acid 

Relevant articles and documents

Hydrolytic Resolution of Tertiary Acetylenic Acetate Esters With the Lipase from Candida Cylindracea

The kinetic resolution of a series of tertiary acetylenic acetate esters using the lipase from Candida cylindracea has been explored.Compounds 6c and the trifluoromethyl acetate 6e have been resolved with high enantiomeric enrichment.Several other tertiary acetate esters carrying a CF3 group have been investigated which proved inert to enzymatic hydrolysis.From these results and published data, we are able to propose a predictive model for identifying the preferred enantiomer of secondary and tertiary trifluoromethyl acetate esters for this lipase.