14195-09-6

Basic information

• Product Name: 2-[(4-methylphenyl)sulfonyl]cyclohexanone
• Synonyms: 2-[(4-methylphenyl)sulfonyl]cyclohexanone
• CAS NO: 14195-09-6
• Molecular Formula: C₁₃H₁₆O₃S
• Molecular Weight: 252.32934
• Mol File: 14195-09-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(4-methylphenyl)sulfonyl]cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-methylphenyl)sulfonyl]cyclohexanone(14195-09-6)
• EPA Substance Registry System: 2-[(4-methylphenyl)sulfonyl]cyclohexanone(14195-09-6)

Safety Data

• Hazardous Substances Data: 14195-09-6(Hazardous Substances Data)

Usage

Type of compound

sulfonyl compound

Structure

cyclohexanone ring substituted with a 4-methylphenyl group

Usage

Different sources of media describe the Usage of 14195-09-6 differently. You can refer to the following data:
1. intermediate in the synthesis of various pharmaceuticals and biologically active molecules
2. building block in the synthesis of other organic compounds

Importance

valuable tool in the field of organic synthesis due to its chemical properties and reactivity.

Upstream product

• 657-84-1 sodium tosylate 
• 108-94-1 cyclohexanone 
• 822-87-7 2-Chlorocyclohexanone 
• 106-45-6 para-thiocresol 
• 98-59-9 p-toluenesulfonyl chloride 
• 37457-03-7 2-(p-Toluenesulfenyl)cyclohexanone 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 104871-67-2 (R)-2-(p-tolylsulfinyl)-1-cyclohexanone 

Downstream Products

• 1680-51-9 6-methyl-1,2,3,4-tetrahydronaphthalene 
• 108-93-0 cyclohexanol 
• 1350558-79-0 2-tosyl-1',3'-dihydrospiro[cyclohexane-1,2'-perimidine] 
• 1350558-95-0 2-(5-tosylpentyl)-1H-benzo[d]imidazole 
• 1138239-56-1 C₂₁H₂₄O₃S 
• 1138239-52-7 10-tosyl-7,8,9,10-tetrahydrobenzo[8]annulen-5(6H)-one 
• 260358-65-4 (+/-)-5-(p-toluenesulfonyl)bicyclo[3.3.1]non-2-en-9-one 
• 260358-64-3 (+/-)-2-allyl-2-(p-toluenesulfonyl)cyclohexanone 
• 67963-06-8 1-(cyclohexylsulfonyl)-4-methylbenzene 
• 14987-95-2 cis-(2-p-Tolylsulfon-cyclohexyl)-tosylat 

Relevant articles and documents

Method for efficiently synthesizing beta-ketone sulfonyl compounds through visible light induction

The invention provides a method for efficiently synthesizing beta-ketone sulfonyl compounds through visible light induction. The method specifically comprises steps as follows: in the presence of an organic solvent and at the room temperature, enol sulfonate compounds are taken as a raw material and react for 1-12 h through induction of visible light under the catalysis action of an organic compound serving as a photocatalyst, and the beta-ketone sulfonyl compounds are prepared. Compared with an existing method, the method has a wide applicable substrate range, a substrate is convenient and easy to obtain, reaction conditions are mild, operation is simple and convenient, the reaction efficiency is high, and the method has huge value in industrial application.

α-chlorination of ketones using p-toluenesulfonyl chloride

Treatment of a variety of ketones with lithium diisopropylamide followed by p-toluenesulfonyl chloride gives α-chloroketones in good yields. In addition, a polymer bound tosyl chloride reagent has also been shown to effect this transformation.