141963-78-2

Upstream product

• 141946-89-6 4-carboxy-2,3-dimethoxy-N,N-dimethylbenzamide 
• 141946-88-5 2,3-dimethoxy-4-methoxycarbonyl-N,N-dimethylbenzamide 
• 75956-63-7 sodium methyl 2,3-dimethoxyterephthalate 
• 75956-64-8 2,3-Dimethoxy-4-(methoxycarbonyl)benzoylchlorid 
• 141946-90-9 N,N',N''-tris<2,3-dimethoxy-4-(N,N-dimethylcarbamoyl)benzoyl>-2,11,20-triaza<3.3.3>paracyclophane 

Downstream Products

• 141946-85-2 N,N',N''-trimethyl-N,N',N''-tris<2,3-dihydroxy-4-(N,N,N-trimethylammoniomethyl)benzyl>-2,11,20-triaza<3.3.3>paracyclophane hexachloride 

Relevant academic research and scientific papers

Azaparacyclophanes with Metal-binding Sites. Part 1. Preparation, Characterization, and Molecular Recognition Behaviour of Hexapus Azaparacyclophane and its Iron(III) Complex

All the catechol moieties of a hexapus triazaparacyclophane having three catechol moieties and six hydrocarbon chains (1) undergo coordination interactions with the iron(III) ion in a 1:1 molar ratio of 1 to iron(III) above pH 6 in an aqueous medium.Two different iron(III) complexes of 1, A and B in a 1:1 molar ratio, are in the high spin iron(III) state as characterized by electronic, EPR and Moessbauer spectroscopy: A is a hexacoordinated mononulear complex with half-protonated catecholato groups, subjected to considerable structural distortion; B is ahexacoordinated mononuclear complex with complete dissociation of all the catechol protons, retaining high structural symmetry.The molecular recognition behaviour of 1 and Fe-complex A toward hydrophobic guest molecules has been investigated in aqueous HEPES and acetate buffers at 30.0 deg C and μ 0.10 mol dm-3.The hexapus cyclophane 1 recognizes organic guests through hydrophobic and electrostatic interactions; anionic and non-ionic quests, 7-hydroxy-8-phenylazonaphthalene-1,3-disulfonate (OG) and 2-hydroxy-1-(2-pyridylazo)naphthalene (PAN), respectively, are incorporated into host 1 with binding constants of the order of 105 dm3 mol-1, while a cationic guest, 2-(p-dimethylaminostyryl)-1-ethylquinolinium (QR), is not included in the host.The guest-binding behaviour of Fe-complex A toward OG and PAN is much enhanced relative to that of 1 as effected by hydrophobic, electrostatic and coordination interactions under conditions identical to those applied to 1; the binding constant for OG is nearly pH-independent in a pH range of 3-8, while that for PAN is pH-dependent because the coordination interaction with the host is subject to change by pH.