1419872-95-9Relevant academic research and scientific papers
S- to N-Acyl transfer in S-acylcysteine isopeptides via 9-, 10-, 12-, and 13-membered cyclic transition states
Bol'shakov, Oleg,Kovacs, Judit,Chahar, Mamta,Ha, Khanh,Khelashvili, Levan,Katritzky, Alan R.
, p. 704 - 709 (2012)
S-Acyl cysteine peptides containing α-, β- or γ-amino acid residues undergo long-range S- to N-acyl transfer to give analogs of native tripeptides and tetrapeptides containing additional carbon atoms in the chain. The ease of intramolecular S→N-acyl transfer relative to intermolecular transacylation is favored increasingly for 91213~10-membered cyclic transition states; the observed order is explained on conformational and intermolecular interaction considerations.
S- to N-Acyl transfer in S-acylcysteine isopeptides via 9-, 10-, 12-, and 13-membered cyclic transition states
Bol'shakov, Oleg,Kovacs, Judit,Chahar, Mamta,Ha, Khanh,Khelashvili, Levan,Katritzky, Alan R.
, p. 704 - 709,6 (2012/12/12)
S-Acyl cysteine peptides containing α-, β- or γ-amino acid residues undergo long-range S- to N-acyl transfer to give analogs of native tripeptides and tetrapeptides containing additional carbon atoms in the chain. The ease of intramolecular S→N-acyl transfer relative to intermolecular transacylation is favored increasingly for 91213~10-membered cyclic transition states; the observed order is explained on conformational and intermolecular interaction considerations.
