141989-40-4Relevant articles and documents
Synthesis and properties of 2-(2-furyl)- and 2-(2-thienyl)-1-methylphenanthro[9,10-d]imidazoles
Pechkin,El'chaninov,Stoyanov
, p. 726 - 730 (2002)
Condensation of 9,10-phenanthrenequinone with 2-furaldehyde and 2-thiophenecarbaldehyde in glacial acetic acid in the presence of ammonium acetate gave 2-(2-furyl)- and 2-(2-thienyl)phenanthro[9,10-d]imidazoles which were converted into the corresponding 1-methyl derivatives. The furan and thiophene rings in the products lose their acidophobic properties. Depending on the conditions, electrophilic substitution reactions in 2-(2-furyl)- and 2-(2-thienyl)phenanthro[9,10-d]imidazoles occur both at the furan (thiophene) and phenanthrene moieties.
INVESTIGATIONS OF 2-SUBSTITUTED IMIDAZOLES. 2. SYNTHESIS AND ELECTROPHILIC SUBSTITUTION OF 1-METHYL-2-(THIENYL-2)IMIDAZOLE. A CONVENIENT METHOD OF METHYLATION OF 2-R-IMIDAZOLES
Stoyanov, V. M.,El'chaninov, M. M.,Pozharskii, A. F.
, p. 1140 - 1144 (2007/10/02)
We have synthesized 2-(thienyl-2)imidazole and its N-methyl derivative.The latter product was obtained by nitration, bromination, acylation, and formylation, occurring as a rule on the thiophene ring.A general method for methylating 2-R-imidazoles with methyl iodide KOH-dimethoxy ethane is proposed.