141996-44-3Relevant academic research and scientific papers
A quaternary ammonium salt [H-dabco][AcO]: As a recyclable and highly efficient catalyst for the one-pot synthesis of β-phosphonomalonates
Yu, Ya-Qin,Xu, Da-Zhen
, p. 28857 - 28863 (2015/04/14)
A simple, green and highly efficient approach for the one-pot three-component synthesis of β-phosphonomalonates has been developed. In the presence of the quaternary ammonium salt catalysts, the β-phosphonomalonates were obtained in excellent yields within short times via tandem Knoevenagel-phospha-Michael reaction. The reaction of aldehydes/ketones, active methylene compounds, and diethyl phosphite performed at room temperature under solvent-free conditions. No column purification is required and the products can be purified by simple crystallization. The catalysts can be easily recovered and reused several times without significant activity loss. This journal is
A practical and highly efficient protocol for multicomponent synthesis of β-phosphonomalononitriles and 2-amino-4H-chromen-4-yl phosphonates using diethylamine as a novel organocatalyst
Kulkarni,Pandurangi,Desai,Wadgaonkar
, p. 745 - 752 (2012/10/30)
Diethylamine has been demonstrated for the first time to be a highly efficient organocatalyst in the solvent-free synthesis of β- phosphonomalononitriles by a three component condensation of aldehyde, malononitrile and dialkyl phosphite at ambient temperature. The applicability of the same catalyst in the synthesis of diethyl (2-amino-3-cyano-chromene-4-yl) phosphonic acid esters has also been described.
REACTION OF ALKYL PHOSPHITES ON SOME DERIVATIVES OF MALONONITRILES
Fahmy, Afaf A.,Ismail, Nabila A.,Hafez, Taghrid S.
, p. 201 - 206 (2007/10/02)
Alkyl phosphites add to carbon-carbon double bonds in malononitriles compounds I and II to give the corresponding phosphonates IIIa,b IVa,b, Va,b and VIa,b respectively.Also, alkyl phosphites add to carbon-nitrogen double bonds in Schiff bases VII and VII
