141996-65-8Relevant academic research and scientific papers
L-aspartic acid bis(trimethylsilyl) ester: A convenient starting material for the acylation of L-aspartic acid
Castano, Ana M.,Echavarren, Antonio M.
, p. 3377 - 3384 (2007/10/02)
Reaction of L-aspartic acid with excess of bis(trimethylsilyl)amine under reflux provides optically pure L-aspartic acid bis(trimethylsilyl) ester in quantitative yield. This silyl ester reacts with a variety of acylating reagens in tetrahydrofuran to give N-protected aspartic acids and dipeptides in good yields without racemization.
Regioselective functionalization of chiral nickelacycles derived from N-protected aspartic and glutamic anhydrides
Castano,Echavarren
, p. 4783 - 4786 (2007/10/02)
The electrophilic cleavage of the nickelacycles resulting from oxidative addition of Ni(o) complexes to N-protected aspartic and glutamic anhydrides, followed by decarbonylation, gives rise regioselectively to derivatives of α- and β-alanine or α- and γ-aminobutyric acid, respectively.
