14200-19-2

Upstream product

• 618-45-1 3-isopropylhydroxybenzene 

Downstream Products

• 103145-11-5 2,4-dichloro-3-isopropyl-6-nitrophenol 
• 14143-32-9 4-chloro-3-ethylphenol 
• 865305-17-5 1-chloro-2-isopropyl-4-methoxy-benzene 
• 865305-16-4 1-chloro-4-isopropyl-2-methoxy-benzene 

Relevant academic research and scientific papers

Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases

Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Diaminopyrimidines as P2X3 and P2X2/3 antagonists

Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.