1420044-33-2Relevant academic research and scientific papers
ANTIVIRAL DRUGS FOR TREATMENT OF ARENA VIRUS INFECTION
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, (2013/08/28)
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole
Dai, Dongcheng,Burgeson, James R.,Gharaibeh, Dima N.,Moore, Amy L.,Larson, Ryan A.,Cerruti, Natasha R.,Amberg, Sean M.,Bolken, Tove C.,Hruby, Dennis E.
, p. 744 - 749 (2013/02/25)
A chemically diverse library of about 400,000 small molecules was screened for antiviral activity against lentiviral pseudotypes with the Lassa virus envelope glycoprotein (LASV GP) gene incorporated. High-throughput screening resulted in discovery of a h
