142044-38-0 Usage
General Description
(+)-cis-5,6-Epoxy-5,6-dihydroquinoline N-oxide is a chemical compound that is an epoxide derivative of quinoline N-oxide. It is a white to yellowish solid with a molecular formula of C9H9NO3. (+-)-cis-5,6-Epoxy-5,6-dihydroquinoline N-oxide is used in organic synthesis and as a reagent in chemical reactions. It is known to possess biological activity and can be used in the preparation of various pharmaceutical compounds. The compound has been found to exhibit potential anticancer and antimalarial properties, making it a valuable compound in medicinal chemistry research. Additionally, it is used as a building block for the synthesis of novel compounds with potential pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 142044-38-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,0,4 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 142044-38:
(8*1)+(7*4)+(6*2)+(5*0)+(4*4)+(3*4)+(2*3)+(1*8)=90
90 % 10 = 0
So 142044-38-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO2/c11-10-5-1-2-6-7(10)3-4-8-9(6)12-8/h1-5,8-9H/t8-,9+/m1/s1
142044-38-0Relevant articles and documents
Arene Oxides of Quinoline: Epoxidation, N-Oxidation and N-Methylation Reactions
Boyd, Derek R.,Davies, R. Jeremy H.,Hamilton, Lynne,McCullough, John J.,Porter, H. Patricia
, p. 2189 - 2192 (2007/10/02)
trans-5,6,7,8-Diepoxy-5,6,7,8-tetrahydroquinoline 5, 5,6-epoxy-5,6-dihydroquinoline 1-oxide 3, 7,8-epoxy-7,8-dihydroquinoline 1-oxide 4 and trans-5,6,7,8-diepoxy-5,6,7,8-tetrahydroquinoline 6 have been formed by oxidation of the corresponding arene oxides of quinoline, 5,6-epoxy-5,6-dihydroquinoline 1 and 7,8-epoxy-7,8-dihydroquinoline 2.The cis-diepoxides, cis-5,6,7,8-diepoxy-5,6,7,8-tetrahydroquinoline 8 and cis-5,6,7,8-diepoxy-5,6,7,8-tetrahydroquinoline 1-oxide 9 were both obtained by a stepwise synthesis from 7,8-epoxy-7,8-dihydroquinoline 2 via the bromohydrin 7.N-Methylation of 5,6-epoxy-5,6-dihydroquinoline 1 and 7,8-epoxy-7,8-dihydroquinoline 2 with methyl trifluoromethanesulfonate yielded the corresponding N-methylquinolinium arene oxide salts 10 and 11.
