1420468-47-8

Basic information

• Product Name: 5,7-dichloro-3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine
• Synonyms: 5,7-dichloro-3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine
• CAS NO: 1420468-47-8
• Molecular Weight: 360.166
• Mol File: 1420468-47-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5,7-dichloro-3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-dichloro-3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine(1420468-47-8)
• EPA Substance Registry System: 5,7-dichloro-3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine(1420468-47-8)

Safety Data

• Hazardous Substances Data: 1420468-47-8(Hazardous Substances Data)

Upstream product

• 1420468-43-4 (2E)-2-[bis(methyloxy)methyl]-3-[2-methyl-3-(trifluoromethyl)phenyl]-2-propenenitrile 
• 1420468-44-5 3,3-bis(methyloxy)-2-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}propanenitrile 
• 1420468-45-6 4-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-amine 
• 878001-20-8 2-methyl-3-(trifluoromethyl)benzaldehyde 
• 1420468-46-7 3-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine-5,7(4H,6H)-dione 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 10025-87-3 trichlorophosphate 

Downstream Products

• 1420468-49-0 3-(2-methyl-3-(trifluoromethyl)benzyl)-5-morpholinopyrazolo[1,5-a]pyrimidin-7-ol 
• 1420468-77-4 4-(7-methoxy-3-(2-methyl-3-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-5-yl)morpholine 
• 1420468-76-3 4-(7-chloro-3-(2-methyl-3-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-5-yl)morpholine 
• 1420468-48-9 C₁₅H₁₁ClF₃N₃O 

Relevant articles and documents

Pyrazolopyrimidine derivatives as PI3 kinase inhibitors

PI3Kβ selective compounds having the structure

PYRAZOLOPYRIMIDINE DERIVATIVES AS PI3 KINASE INHIBITORS

The present invention relates to compounds of formula (I) in which R1, R2, R3 and n have the meaning given in the specification and also relates to the use of these pyrazolopyrimidine derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3'OΗ kinase family (hereinafter PI3 kinases), wherein the compounds of formula (I) are described as selective inhibitors of PI3K[beta] activity.