1420476-84-1

Basic information

• Product Name: 7-bromo-2-phenethyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione
• Synonyms: 7-bromo-2-phenethyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione
• CAS NO: 1420476-84-1
• Molecular Weight: 347.211
• Mol File: 1420476-84-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-bromo-2-phenethyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-2-phenethyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione(1420476-84-1)
• EPA Substance Registry System: 7-bromo-2-phenethyl-3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)-dione(1420476-84-1)

Safety Data

• Hazardous Substances Data: 1420476-84-1(Hazardous Substances Data)

Upstream product

• 2842-37-7 2-(phenethylamino)ethanol 
• 1214385-51-9 5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylic acid 

Relevant articles and documents

Synthesis of pyridopyrazine-1,6-diones from 6-hydroxypicolinic acids via a one-pot coupling/cyclization reaction

A facile one-pot synthesis of 3,4-dihydro-1H-pyrido[1,2-a]pyrazine-1,6(2H)- diones (pyridopyrazine-1,6-diones) has been developed which employs a sequential coupling/cyclization reaction of 6-hydroxypicolinic acids and β-hydroxylamines. The transformation proceeds in good yield under mild conditions using O-(7-aza-1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HATU) to both carry out the amide formation and activate the hydroxyl group for intramolecular alkylation.