142074-12-2

Basic information

• Product Name: Imidazo[1,2-b]pyridazine, 2-(4-methylphenyl)-6-(propylthio)-
• CAS NO: 142074-12-2
• Molecular Formula: C16H17N3S
• Molecular Weight: 283.397
• Mol File: 142074-12-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Imidazo[1,2-b]pyridazine, 2-(4-methylphenyl)-6-(propylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-b]pyridazine, 2-(4-methylphenyl)-6-(propylthio)-(142074-12-2)
• EPA Substance Registry System: Imidazo[1,2-b]pyridazine, 2-(4-methylphenyl)-6-(propylthio)-(142074-12-2)

Safety Data

• Hazardous Substances Data: 142074-12-2(Hazardous Substances Data)

Upstream product

• 113121-36-1 6-propylsulfanylpyridazin-3-amine 
• 619-41-0 4-(bromoacetyl)toluene 

Downstream Products

• 142074-14-4 3-benzamidomethyl-6-propythio-2-(4'-tolyl)imidazo<1,2-b>pyridazine 

Relevant articles and documents

Imidazopyridazines. XII. Syntheses and Central Nervous System Activities of Some Substituted Imidazopyridazines and Related Imidazopyridines, Imidazopyrimidines and Imidazopyrazines

Syntheses are reported for some 6-chloro(alkoxy, alkylthio and phenylthio)-3-benzamidomethyl-(acetamidomethyl and methoxy)-2-arylimidazopyridines and some corresponding imidazo-pyridazines, imidazopyrimidines and imidazopyrazines.IC50 values (or percentage displacement) are reported and discussed for the displacement of 3H>diazepam from rat brain membrane by each of these compounds.The imidazopyridines were generally less potent than the imidazopyridazines but considerably more potent than the corresponding imidazopyrimidines or imidazopyrazines.Substitution of 2-aryl group by a 2-alkyl group in imidazopyridazines led to a significant loss of activity.