142074-85-9Relevant academic research and scientific papers
Synthesis and Insecticidal Activity of 4-(Aminomethyl)-2H-1-benzothiopyran-2-ones (Thiocoumarins) and Related Compounds
Nakazumi, Hiroyuki,Kobara, Yuzoh,Kitao, Teijiro
, p. 135 - 139 (2007/10/02)
Bromination of 4-methyl-2H-1-benzothiopyran-2-ones (4-methylthiocoumarins) with bromine under irradiation of high-pressure mercury lamp gave 3-bromo-4-methylthiocoumarin, which reacted with secondary amine to give 4-(aminomethyl)thiocoumarins.The structure was determined by X-ray crystallographic analysis.A series of 4-methylthiocoumarin and related compounds were tested for insecticidal activity, and 4,6-dimethylthiocoumarin shows the most significant insecticidal activity against Nilaparvata lugens and Aphis gossypii.An introduction of an aminomethyl group inthiocoumarin results in improvement of activity against Tetranychus urticae and Spodoptera litura.
