142075-19-2

Upstream product

• 142075-18-1 (1R,2R,5R,6R,7R)-6-(tert-Butyl-dimethyl-silanyloxy)-2,5,7-trimethyl-cyclohept-3-enol 
• 824-94-2 p-methoxybenzyl chloride 
• 129467-82-9 (1RS,2RS,3RS,4RS,7RS)-2,4,7-trimethyl-cyclohept-5-ene-1,3-diol 
• 96691-93-9 (1R,2R,3r,4S,5S)-2,4-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-ol 

Downstream Products

• 142075-20-5 (2R,3R,4R,5R,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4,6-trimethyl-heptane-1,7-diol 

Relevant academic research and scientific papers

The effect of remote oxygens on the ring-opening reactions of oxabicyclic compounds with organolithium reagents. Synthesis of the C21-C27 segment of rifamycin S

The reactivity of several related oxabicyclo[3.2.1]octenes toward ring-opening was found to depend on the stereochemistry of a remote hydroxyl group. It was also found that attenuation of the reactivity occurred upon protection of the remote alcohol.