14208-10-7Relevant articles and documents
Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications
Musilek, Kamil,Komloova, Marketa,Zavadova, Vlasta,Holas, Ondrej,Hrabinova, Martina,Pohanka, Miroslav,Dohnal, Vlastimil,Nachon, Florian,Dolezal, Martin,Kuca, Kamil,Jung, Young-Sik
body text, p. 1763 - 1766 (2010/08/21)
Reversible inhibitors (e.g., pyridostigmine bromide, neostigmine bromide) of carbamate origin are used in the early treatment of Myasthenia gravis (MG) to block acetylcholinesterase (AChE) native function and conserve efficient amount of acetylcholine for
Binding selectivity of cucurbit[7]uril: Bis(pyridinium)-1,4-xylylene versus 4,4′-bipyridinium guest sites
Sindelar, Vladimir,Moon, Kwangyul,Kaifer, Angel E.
, p. 2665 - 2668 (2007/10/03)
The binding interactions between the host cucurbit[7]uril (CB7) and a series of linear guests containing bis(pyridinium)-1,4-xylylene and/or 4,4′-bipyridinium residues were investigated by 1H NMR spectroscopy. CB7 was found to exhibit considerable binding selectivity for bis-(pyridinium)-1,4-xylylene over 4,4′-bipyridinium sites. New pseudo-rotaxane and rotaxane compounds were synthesized utilizing the host-guest interactions between CB7 and the surveyed guests.