1421014-36-9

Basic information

• Product Name: (2S,3R)-2-(4-fluorophenyl)-3-isopropyl-1-(4-nitrophenylsulfonyl)aziridine
• Synonyms: (2S,3R)-2-(4-fluorophenyl)-3-isopropyl-1-(4-nitrophenylsulfonyl)aziridine
• CAS NO: 1421014-36-9
• Molecular Weight: 364.397
• Mol File: 1421014-36-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R)-2-(4-fluorophenyl)-3-isopropyl-1-(4-nitrophenylsulfonyl)aziridine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-2-(4-fluorophenyl)-3-isopropyl-1-(4-nitrophenylsulfonyl)aziridine(1421014-36-9)
• EPA Substance Registry System: (2S,3R)-2-(4-fluorophenyl)-3-isopropyl-1-(4-nitrophenylsulfonyl)aziridine(1421014-36-9)

Safety Data

• Hazardous Substances Data: 1421014-36-9(Hazardous Substances Data)

Upstream product

• 1421117-67-0 (1S,2R)-2-amino-1-(4-fluorophenyl)-3-methylbutan-1-ol 
• 1421014-27-8 (2S,3R)-2-(4-fluorophenyl)-3-isopropylaziridine 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 1421117-74-9 (1R,2R)-1-chloro-1-(4-fluorophenyl)-3-methylbutan-2-amine 

Downstream Products

• 1421014-46-1 (1R,2R)-15N-(1-(benzylamino)-1-(4-fluorophenyl)-3-methylbutan-2-yl)-4-nitrobenzenesulfonamide 
• 1421014-57-4 (1R,2R)-15N₁-benzyl-1-(4-fluorophenyl)-3-methylbutane-1,2-diamine 

Relevant articles and documents

Synthesis of 15N-labeled vicinal diamines through N-activated chiral aziridines: Tools for the NMR study of platinum-based anticancer compounds

A new method for the synthesis of 15N-labeled chiral β-diamines from a common precursor, either optically pure amino acids or anti-β-amino alcohols, is reported. The two diastereomeric series of vicinal diamines are produced through the nucleophilic ring opening of activated chiral aziridines. 15N was introduced by means of [ 15N]-benzylamine, prepared from 15NH4Cl. The final compounds are highly valuable because [1H-15N] NMR is considered a powerful tool for studying the chemical properties of platinum-based complexes.