1421023-54-2Relevant academic research and scientific papers
Synthesis, antibacterial, antielastase, antiurease and antioxidant activities of new methoxy substitued bis-1,2,4-triazole derivatives
Sokmen, Bahar Bilgin,Gumrukcuoglu, Nurhan,Ugras, Serpil,Ugras, Halil Ibrahim,Yanardag, Refiye
, p. 72 - 77 (2013/04/23)
The methoxy substitued two novel bis triazole-schiff bases (6 a-b) were synthesized with 4-amino-3,5-diethyl-4H-1,2,4-triazole and various bis-aldehydes. Their amine derivatives prepared by reduced with NaBH4 (5 a-b). The obtained products 6 a-b and 7 a-b were identified by FT-IR, H-NMR, 13C-NMR. The bis triazole-schiff bases and amine derivatives were tested for antimicrobial activity using the agar diffusion technique against 11 bacteria. The synthesized compounds (6 a-b and 7 a-b) were screened for their antielastase, antiurease and antioxidant activities. The resuts showed that the synthesized compounds (6 a-b and 7 a-b) had effective antielastase and antiurease activities.
