1421313-18-9

Upstream product

• 100-44-7 benzyl chloride 
• 1365537-25-2 4-benzyloxy-6-hydroxy-2-(methoxymethoxy)acetophenone 
• 71386-98-6 2',4'-dihydroxy-6'-(methoxymethoxy)acetophenone 
• 1429227-32-6 4-(t-butyldimethylsilyloxy)-6-hydroxy-2-(methoxymethoxy)acetophenone 
• 139140-13-9 1-{4-[(tert-butyldimethylsilyl)oxy]-2,6-dihydroxyphenyl}ethan-1-one 
• 1447605-66-4 C₃₈H₃₄O₇ 

Downstream Products

• 1421313-37-2 C₄₅H₄₂O₇ 
• 1421313-28-1 C₁₅H₁₄O₉S*H₃N 
• 223614-70-8 epicatechin-5-O-β-D-glucuronide 
• 1421313-35-0 C₄₉H₄₆O₁₂ 
• 1421313-34-9 C₅₆H₅₄O₁₅ 
• 1429422-58-1 C₄₃H₃₈O₆ 

Relevant academic research and scientific papers

Enantioselective synthesis of orthogonally protected (2R,3R)-(-)- epicatechin derivatives, key intermediates in the de novo chemical synthesis of (-)-epicatechin glucuronides and sulfates

Ten orthogonally protected (-)-epicatechin and 3′- or 4′-O-methyl-(-)-epicatechin derivatives were prepared in a regiospecific and enantioselective manner. For each orthogonally protected (-)-epicatechin derivative, one specific phenolic hydroxyl was protected with a methoxymethyl (MOM) or p-methoxybenyzl (PMB) group and the remainder were protected as benzyl ethers. These uniquely protected (-)-epicatechin derivatives were designed to facilitate the regiospecific installation of a glucuronic acid or sulfate unit onto (-)-epicatechin after selective removal of the MOM or PMB protecting group to provide authentic standards of (-)-epicatechin glucuronides and sulfates.