1421332-37-7Relevant articles and documents
Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases
Chuck, Chi-Pang,Chen, Chao,Ke, Zhihai,Chi-Cheong Wan, David,Chow, Hak-Fun,Wong, Kam-Bo
, p. 1 - 6 (2013/03/13)
Coronaviral infection is associated with up to 5% of respiratory tract diseases. The 3C-like protease (3CLpro) of coronaviruses is required for proteolytic processing of polyproteins and viral replication, and is a promising target for the deve