1421353-97-0Relevant academic research and scientific papers
Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group
Anderson, Niall A.,Fallon, Brendan J.,Valverde, Elena,MacDonald, Simon J. F.,Pritchard, John M.,Suckling, Colin J.,Watson, Allan J. B.
, p. 2817 - 2821 (2013/02/21)
Application of the Miyaura-Hayashi rhodium-catalysed addition of aryl boronic acids to acyclic unsaturated esters featuring basic centres to yield γ-amino butyric acids incorporating a substituted β-phenyl group is described. Unoptimised isolated yields and enantiomeric excesses vary from moderate to excellent, and the method tolerates a variety of substitution patterns and a range of functionality. Copyright
