1421364-73-9Relevant academic research and scientific papers
Coupling of two multistep catalytic cycles for the one-pot synthesis of propargylamines from alcohols and primary amines on a nanoparticulated gold catalyst
Corma, Avelino,Navas, Javier,Sabater, Maria J.
, p. 14150 - 14156 (2012)
A one-pot reaction was performed with a nanoparticulated gold catalyst. A secondary amine is formed through N-monoalkylation of a primary amine with an alcohol by a borrowing hydrogen methodology in a three-step reaction. The secondary amine formed enters into a second A3-coupling cycle to give propargylamines. The multistep reaction requires a gold species formed and stabilized on a ceria surface. Copyright
The synthesis of sterically hindered amines by a direct reductive amination of ketones
Yagafarov, Niyaz Z.,Kolesnikov, Pavel N.,Usanov, Dmitry L.,Novikov, Valentin V.,Nelyubina, Yulia V.,Chusov, Denis
supporting information, p. 1397 - 1400 (2016/01/25)
An atom-economical methodology for the synthesis of sterically hindered tertiary amines was developed, which is based on complementary Rh- and Ru-catalyzed direct reductive amination of ketones with primary and secondary amines using carbon monoxide as a deoxygenating agent.
