1421370-58-2Relevant academic research and scientific papers
Rapid and stereoselective synthesis of spirocyclic ethers via the intramolecular Piancatelli rearrangement
Palmer, Leoni I.,De Alaniz, Javier Read
supporting information, p. 476 - 479 (2013/04/10)
The first example of a Piancatelli rearrangement of alcohols is demonstrated utilizing dysprosium(III) triflate as a catalyst to access oxaspirocycles in a highly diastereoselective manner. The cascade reaction constructs the spirocyclic ether ring system and the tertiary stereocenter in a single operation and is experimentally easy to perform.
