1421454-91-2Relevant academic research and scientific papers
Novel malyngamide structural analogs: Synthesis and biological evaluation
Reddy, G. Venkateswar,Kumar, T. Vijaya,Siva,Babu, K. Suresh,Srinivas,Sehar, Irum,Saxena,Rao, J. Madhusudana
, p. 4581 - 4591 (2013/09/23)
In the course of our search for new anticancer agents, a series of novel malyngamide derivatives were synthesized by sharpless asymmetric epoxidation, followed by Julia-Kocinski olefination reactions as key reaction sequence. Anticancer activities of all these derivatives were screened against IMR-32, SF-295, SKNSH, HeLa, Colon-502713, SW-620, and Hop-62 cell lines for the first time.
