1421470-68-9Relevant articles and documents
Synthesis of quinolones by nickel-catalyzed cycloaddition via elimination of nitrile
Nakai, Kenichiro,Kurahashi, Takuya,Matsubara, Seijiro
supporting information, p. 856 - 859 (2013/03/28)
Substituted quinolones were efficiently synthesized via the nickel-catalyzed cycloaddition of o-cyanophenylbenzamide derivatives with alkynes. The reaction involves elimination of a nitrile group by cleavage of the two independent aryl-cyano and aryl-carbonyl C-C bonds of the amides.