1421605-75-5Relevant articles and documents
Synthesis of 2H-pyrrolo[3,4-C]quinoline via an Aldol/Van Leusen/Staudinger/aza-Wittig sequence
Shi, Yu-Qing,Liao, Li-De,He, Ping,Hu, Yang-Gen,Cheng, Hua,Wang, Song,Wu, Jun-Jun
supporting information, p. 1357 - 1363 (2016/09/03)
An aldol/van Leusen/Staudinger/aza-Wittig reaction for the preparation of the derivatives of 2H-pyrrolo[3,4-c]quinolines from 2-azidobenzaldehyde, acetyl compounds, and tosylmethyl isocyanide was developed. The process involves an aldol condensation of 2-
3-Phenacylideneoxindoles with tosylmethyl isocyanide and MeOH through C-C bond cleavage: Facile synthesis of pyrrole and 2H-pyrrolo[3,4-c]quinoline derivatives
Wang, Rong,Xu, Xiao-Ping,Meng, Hua,Wang, Shun-Yi,Ji, Shun-Jun
, p. 1761 - 1766 (2013/03/14)
A novel reaction of 3-phenacylideneoxindoles (1) with tosylmethyl isocyanide (2a) and MeOH through C-C bond cleavage has been developed. The reaction proceeded under mild conditions, providing a powerful synthetic tool for the construction of pyrrole derivatives (3) from easily accessible starting materials and synthesis of 2H-pyrrolo[3,4-c]quinolines (4) by further dehydration of 3.