1421700-41-5

Basic information

• Product Name: 1H-indole-2,3-dione 3-(N-phenylsemicarbazone)
• Synonyms: 1H-indole-2,3-dione 3-(N-phenylsemicarbazone)
• CAS NO: 1421700-41-5
• Molecular Formula: C₁₅H₁₂N₄O₂
• Molecular Weight: 280.28138
• Mol File: 1421700-41-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-indole-2,3-dione 3-(N-phenylsemicarbazone)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-indole-2,3-dione 3-(N-phenylsemicarbazone)(1421700-41-5)
• EPA Substance Registry System: 1H-indole-2,3-dione 3-(N-phenylsemicarbazone)(1421700-41-5)

Safety Data

• Hazardous Substances Data: 1421700-41-5(Hazardous Substances Data)

Upstream product

• 91-56-5 indole-2,3-dione 
• 537-47-3 4-phenyl-semicarbazide 
• 2040-76-8 phenylcarbamic acid chloride 
• 62-53-3 aniline 

Relevant articles and documents

Light initiated E-Z and Z-E isomerization of isatinphenylsemicarbazones: Tautomeric equilibrium effect

The light and thermally initiated mutual E- and Z-isomer transformations of two efficient isatin N-phenylsemicarbazone colorimetric sensors for strongly basic anions differing in sensitivity, selectivity and sensing mechanism were investigated in solvents

Isatinphenylsemicarbazones as efficient colorimetric sensors for fluoride and acetate anions - Anions induce tautomerism

The anion induced tautomerism of isatin-3-4-phenyl(semicarbazone) derivatives is studied herein. The interaction of F-, AcO -, H2PO4-, Br- or HSO4- anions with E and Z isomers of isatin-3-4-phenyl(semicarbazone) and N-methylisatin-3-4- phenyl(semicarbazone) as sensors influences the tautomeric equilibrium of these sensors in the liquid phase. This tautomeric equilibrium is affected by (1) the inter- and intra-molecular interactions' modulation of isatinphenylsemicarbazone molecules due to the anion induced change in the solvation shell of receptor molecules and (2) the sensor-anion interaction with the urea hydrogens. The acid-base properties of anions and the difference in sensor structure influence the equilibrium ratio of the individual tautomeric forms. Here, the tautomeric equilibrium changes were indicated by naked-eye experiment, UV-VIS spectral and 1H NMR titration, resulting in confirmation that appropriate selection of experimental conditions leads to a high degree of sensor selectivity for some investigated anions. Sensors' E and Z isomers differ in sensitivity, selectivity and sensing mechanism. Detection of F- or CH3COO- anions at high weakly basic anions' excess is possible.