1421747-19-4

Basic information

• Product Name: N-Hydroxylorcaserin
• CAS NO: 1421747-19-4
• Molecular Weight: 211.691
• Mol File: 1421747-19-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Hydroxylorcaserin(CAS DataBase Reference)
• NIST Chemistry Reference: N-Hydroxylorcaserin(1421747-19-4)
• EPA Substance Registry System: N-Hydroxylorcaserin(1421747-19-4)

Safety Data

• Hazardous Substances Data: 1421747-19-4(Hazardous Substances Data)

Usage

Uses

N-Hydroxy Lorcaserin is a metabolite of Lorcaserin (L469890, HCl); a novel selective 5-HT2C-receptor agonist for the treatment of obesity.

Upstream product

• 846589-98-8 Lorcaserin hydrochloride 

Relevant articles and documents

Late Stage Functionalization of Secondary Amines via a Cobalt-Catalyzed Electrophilic Amination of Organozinc Reagents

A general preparation of polyfunctional hydroxylamine benzoates from the corresponding secondary amines is reported. This convenient synthesis allows the setup of a late-stage functionalization of various secondary amines, including pharmaceuticals and peptidic derivatives. Thus, a cross-coupling of hydroxylamine benzoates with various alkyl-, aryl-, and heteroaryl-zinc chlorides in the presence of 5 mol % CoCl2 (25 °C, 2 h) provides a range of polyfunctional tertiary amines. This method was used to prepare penfluridol and gepirone.