1421770-47-9Relevant academic research and scientific papers
Arylation of adamantanamines: VI. Palladium-catalyzed arylation of amines and diamines of the adamantane series with 3-bromopyridine
Averin,Baranova,Abel,Kovalev,Buryak,Butov,Savelyev,Orlinson,Novakov,Beletskaya
, p. 1 - 7 (2013)
Palladium-catalyzed amination of 3-bromopyridine with amines of the adamantane series in the presence of Pd(dba)2/L [L = 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl or 2-dimethylamino- 2′-dicyclohexylphosphinobiphenyl] gave the desired N-(pyridin-3-yl)- substituted amines in 74-97% yields. Diamines of the adamantane series reacted with 2 equiv of 3-bromopyridine in a complicated fashion to produce mono- and triaryl-substituted derivatives as by-products, while the yields of N,N′-diarylation products were 18-56%.
