1421790-28-4

Upstream product

• 97026-71-6 (3-(4-chlorophenyl)-5-methyl)isoxazole-4-carboxylic acid ethyl ester 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 3848-36-0 4-chlorobenzaldoxime 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1421790-21-7 2-(5-methyl-3-(4-chlorophenyl)isoxazol-4-yl)-5-(4-methoxyphenylamino)-1,3,4-oxdiazole 
• 1421790-22-8 2-(5-methyl-3-(4-chlorophenyl)isoxazol-4-yl)-5-(4-chlorophenylamino)-1,3,4-oxdiazole 
• 1421790-23-9 2-(5-methyl-3-(4-chlorophenyl)isoxazol-4-yl)-5-(4-bromophenylamino)-1,3,4-oxdiazole 
• 1421790-30-8 C₁₈H₁₅ClN₄O₂S 
• 1421790-31-9 C₁₉H₁₇ClN₄O₃S 
• 1421790-32-0 C₁₈H₁₄Cl₂N₄O₂S 
• 1421790-33-1 C₁₈H₁₄BrClN₄O₂S 

Relevant academic research and scientific papers

Design, docking and synthesis of novel bromo isatin incorporated isoxazole derivatives as vegfr-2 inhibitors

Objective: To design, synthesize, in vitro Vascular Endothelial Growth Factor Receptor (VEGFR-2) assay, antiproliferative activity an Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) studies of some novel bromoisatin incorporated isoxa

Synthesis and biological evaluation of novel 2-(substituted isoxazol-4-yl)-5-arylamino-1,3,4-oxadiazoles

A series of 2-(5-methyl-3-(4-chloro/trifluoromethylphenyl)isoxazol-4-yl)-5- arylamino-1,3,4-oxadiazoles were synthesized from 4-chloro/trifluoromethyl benzaldehyde, ethyl acetoacetate, hydroxylamine hydrochloride, hydrazine hydrate, and aryl isocyanate by