1421844-69-0Relevant articles and documents
Three-component domino reactions for regioselective formation of bis-indole derivatives
Fu, Li-Ping,Shi, Qing-Qing,Shi, Yu,Jiang, Bo,Tu, Shu-Jiang
, p. 135 - 140 (2013)
A microwave-assisted regioselective reaction dealing with arylglyoxal monohydrate, diverse N-aryl enaminones, and indoles to achieve 3,2′- and 3,3′-bis-indoles by varying a substituted indole substrate is reported. The 2-unsubstituted indoles resulted in the 3,2′-bis-indole skeleton, whereas indoles bearing a methyl or phenyl group at C2 led to the 3,3′-bis-indoles with simultaneous formation of three sigma-bonds. The procedures feature excellent regioselectivity, short reaction times, convenient one-pot manner, and operational simplicity.
