1421846-93-6

Basic information

• Product Name: 1-({2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}acetyl)piperidin-4-one
• Synonyms: 1-({2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}acetyl)piperidin-4-one
• CAS NO: 1421846-93-6
• Molecular Weight: 440.542
• Mol File: 1421846-93-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-({2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}acetyl)piperidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-({2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}acetyl)piperidin-4-one(1421846-93-6)
• EPA Substance Registry System: 1-({2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}acetyl)piperidin-4-one(1421846-93-6)

Safety Data

• Hazardous Substances Data: 1421846-93-6(Hazardous Substances Data)

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 1421848-76-1 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid 
• 40064-34-4 4-piperidone monohydrochloride monohydrate 
• 1421848-75-0 ethyl 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetate 
• 1421848-74-9 1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazole-4-carbothioamide 
• 1421848-73-8 1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazole-4-carboxamide 
• 936084-44-5 ethyl 1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazole-4-carboxylate 
• 1999-00-4 ethyl 3-(4'-fluorophenyl)-3-oxopropionate 

Relevant articles and documents

HETEROCYCLIC COMPOUND

Provided is a heterocyclic compound having an RORγt inhibitory activity. A compound represented by the formula (I): wherein ring A is an optionally substituted cyclic group, Q is a bond, optionally substituted C1-10 alkylene, optionally substituted C2-10 alkenylene, or optionally substituted C2-10 alkynylene, R1 is a substituent, ring B is a thiazole ring, an isothiazole ring or a dihydrothiazole ring, each of which is optionally further substituted by a substituent in addition to R2, and R2 is an optionally substituted cyclyl-carbonyl-C1-6 alkyl group, an optionally substituted aminocarbonyl-C1-6 alkyl group, an optionally substituted cyclyl-C1-6 alkyl group, an optionally substituted cyclyl-C1-6 alkylamino-carbonyl group, an optionally substituted aminocarbonyl-C2-6 alkenyl group, an optionally substituted C1-6 alkylcarbonylamino-C1-6 alkyl group, an optionally substituted cyclyl-aminocarbonyl group, an optionally substituted cyclyl-carbonyl group or an optionally substituted non-aromatic heterocyclic group, or a salt thereof.