1421919-05-2

Upstream product

• 1421919-04-1 ethyl 4-benzyl-6-methoxychroman-3-ylcarbamate 
• 1421919-03-0 ethyl (4-benzylidene-6-methoxychroman-3-yl)carbamate 
• 1421919-02-9 ethyl (4-benzyl-4-hydroxy-6-methoxychroman-3-yl)carbamate 
• 1421919-01-8 ethyl (6-methoxy-4-oxochroman-3-yl)carbamate 
• 22406-60-6 3-amino-6-methoxychroman-4-one hydrochloride 
• 1421919-00-7 (Z)-6-methoxychroman-4-one O-tosyl oxime 

Downstream Products

• 1421919-08-5 ethyl 4-benzyl-6-(2-(1-methyl-1H-pyrazole-4-sulfonamido)ethoxy)chroman-3-ylcarbamate 
• 1421919-10-9 ethyl 4-benzyl-6-cyanochroman-3-ylcarbamate 
• 1421919-11-0 (4-benzyl-3-(ethoxycarbonylamino)chroman-6-yl)methanaminium chloride 
• 1421919-12-1 ethyl 4-benzyl-6-((1-methyl-1H-imidazole-4-sulfonamido)methyl)-chroman-3-ylcarbamate 
• 1421919-06-3 [4-benzyl-6-(2-tert-butoxycarbonylamino-ethoxy)-chroman-3-yl]-carbamic acid ethyl ester 
• 1421919-09-6 4-benzyl-3-(ethoxycarbonylamino)chroman-6-yltrifluoromethanesulfonate 

Relevant academic research and scientific papers

Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy

The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I) or a physiologically tolerated salt thereof The invention relates to pharmaceutical compositions comprising such aminoch

AMINOCHROMANE, AMINOTHIOCHROMANE AND AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY

The present invention relates to aminochromane, aminothiochromane and 1,2,3,4-tetrahydroquinoline derivatives of the formula (I), or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors