1421933-33-6 Usage
Uses
Used in Pharmaceutical Industry:
S-acetyl-PEG3-acid is used as a molecular building block for the development of novel pharmaceuticals. The ability to form amide bonds with primary amines allows for the creation of conjugates with improved pharmacokinetic properties, such as enhanced solubility, stability, and bioavailability. The thiol moiety generated after deprotection can also be utilized for further functionalization or to form disulfide bonds with other molecules, providing additional opportunities for drug design and optimization.
Used in Drug Delivery Systems:
In the field of drug delivery, S-acetyl-PEG3-acid serves as a versatile component for the design of targeted and controlled release systems. The hydrophilic PEG linker can be used to improve the solubility and circulation time of drug carriers, while the reactive functional groups enable the attachment of therapeutic agents or targeting ligands. This can lead to the development of more effective and safer drug delivery platforms with enhanced targeting and reduced side effects.
Used in Bioconjugation and Protein Engineering:
S-acetyl-PEG3-acid is used as a bioconjugation agent for the modification of proteins, peptides, and other biomolecules. The carboxylic acid can be used to form stable amide bonds with primary amines on the target molecule, while the thiol moiety generated after deprotection can be employed for disulfide bond formation or further functionalization. This allows for the creation of protein conjugates with altered properties, such as improved stability, solubility, or bioactivity, which can be useful in various biotechnological and therapeutic applications.
Used in Diagnostics and Imaging:
S-acetyl-PEG3-acid can be utilized in the development of diagnostic and imaging agents. The hydrophilic PEG linker can improve the pharmacokinetic properties of imaging agents, while the reactive functional groups can be used to attach imaging moieties or targeting ligands. This can lead to the creation of more effective diagnostic tools with enhanced targeting and reduced background signal.
Check Digit Verification of cas no
The CAS Registry Mumber 1421933-33-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,9,3 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1421933-33:
(9*1)+(8*4)+(7*2)+(6*1)+(5*9)+(4*3)+(3*3)+(2*3)+(1*3)=136
136 % 10 = 6
So 1421933-33-6 is a valid CAS Registry Number.
1421933-33-6Relevant academic research and scientific papers
Trehalose-based neuroprotective autophagy inducers
Arosio, Daniela,Assoni, Giulia,Colombo, Eleonora,Frapporti, Giulia,Gornati, Davide,Perez-Carrion, Maria Dolores,Piccoli, Giovanni,Polito, Laura,Seneci, Pierfausto
supporting information, (2021/03/23)
A small set of trehalose-centered putative autophagy inducers was rationally designed and synthesized, with the aim to identify more potent and bioavailable autophagy inducers than free trehalose, and to acquire information about their molecular mechanism
