1421933-39-2

Basic information

• Product Name: Bromoacetamido-PEG3 -Boc-amine
• Synonyms: Bromoacetamido-PEG3 -Boc-amine;Bromoacetamido-PEG3-NH-Boc
• CAS NO: 1421933-39-2
• Molecular Formula: C15H29BrN2O6
• Molecular Weight: 413.30456
• Mol File: 1421933-39-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bromoacetamido-PEG3 -Boc-amine(CAS DataBase Reference)
• NIST Chemistry Reference: Bromoacetamido-PEG3 -Boc-amine(1421933-39-2)
• EPA Substance Registry System: Bromoacetamido-PEG3 -Boc-amine(1421933-39-2)

Safety Data

• Hazardous Substances Data: 1421933-39-2(Hazardous Substances Data)

Usage

Description

Bromoacetamido-PEG3-Boc-amine is a PEG (polyethylene glycol) linker that features a Boc (tert-butyloxycarbonyl) protected amine and a bromide group. This molecule is designed to enhance solubility in aqueous media due to the hydrophilic PEG spacer. The Boc protection allows for mild acidic deprotection of the amine, while the bromide serves as an effective leaving group for nucleophilic substitution reactions, making it a versatile building block in chemical and biological applications.

Uses

Used in Chemical Synthesis:
Bromoacetamido-PEG3-Boc-amine is used as a synthetic building block for the creation of various bioactive molecules and conjugates. The application reason is its ability to facilitate nucleophilic substitution reactions, allowing for the attachment of different functional groups to the PEG linker.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Bromoacetamido-PEG3-Boc-amine is used as a component in the design of drug delivery systems. The application reason is its hydrophilic PEG spacer, which can improve the solubility and bioavailability of therapeutic agents, as well as the Boc protected amine, which can be used for further functionalization and targeting of specific biological receptors.
Used in Bioconjugation:
Bromoacetamido-PEG3-Boc-amine is used as a bioconjugation agent for the attachment of biologically active molecules, such as peptides, proteins, or other biomolecules, to PEGylated structures. The application reason is the bromide group's reactivity in nucleophilic substitution reactions, enabling the formation of stable covalent bonds with target molecules.
Used in Diagnostics:
In the field of diagnostics, Bromoacetamido-PEG3-Boc-amine is used as a component in the development of imaging agents and sensors. The application reason is its ability to be functionalized with various detection moieties, such as fluorescent tags or radiolabels, while maintaining the hydrophilic and biocompatible properties of the PEG linker.
Used in Material Science:
In material science, Bromoacetamido-PEG3-Boc-amine is used as a modifier to improve the properties of polymers and other materials. The application reason is its potential to enhance solubility, biocompatibility, and the ability to incorporate functional groups that can interact with specific biological targets or environmental conditions.