1421947-25-2

Basic information

• Product Name: 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2-iodo-3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-benzyl ester
• Synonyms: 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2-iodo-3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-benzyl ester
• CAS NO: 1421947-25-2
• Molecular Weight: 619.497
• Mol File: 1421947-25-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2-iodo-3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2-iodo-3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-benzyl ester(1421947-25-2)
• EPA Substance Registry System: 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2-iodo-3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-benzyl ester(1421947-25-2)

Safety Data

• Hazardous Substances Data: 1421947-25-2(Hazardous Substances Data)

Upstream product

• 6089-04-9 3-(tetrahydropyran-2'-yloxy)propyne 
• 1421947-21-8 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2,3-diiodo-benzyl ester 
• 1421947-17-2 1-bromomethyl-2,3-diiodobenzene 
• 1608-48-6 3-Methyl-1,2-diiodobenzene 

Downstream Products

• 1421947-29-6 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-2-trimethylsilanylethynyl-benzyl ester 
• 1421947-33-2 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 2-ethynyl-3-[3-(tetrahydro-pyran-2-yloxy)-prop-1-ynyl]-benzyl ester 
• 1421947-40-1 C₄₂H₄₀N₂O₆S 
• 1421947-76-3 C₄₃H₄₄N₂O₉S₂ 
• 1421947-72-9 2-tert-butoxycarbonylamino-3-phenyl-propionic acid 3-(3-hydroxy-prop-1-ynyl)-2-{4-phenyl-3-[(toluene-4-sulfonylamino)-methyl]-but-3-en-1-ynyl}-benzyl ester 
• 1421947-68-3 C₄₇H₅₀N₂O₈S 

Relevant articles and documents

Exploring the scope of Bergman Cyclization mediated cascade reaction of alkenyl enediynes: Synthesis of [5]helicene and amino acid appended [4]helicenes

Bergman Cyclization mediated cascade radical process is employed for the synthesis of [5]helicenes as well as diastereoselective mixtures of chiral amino acid appended [4]helicenes. Maximum selectivity (2.5:1) was found in case of l-leucine attached cyclic enediyne. Mechanistic considerations for this tandem radical reaction revealed that the major pathway probably involved quenching of the biradical, formed after aryl radical addition to pendant aromatic ring, by the solvent followed by aromatization. Intramolecular H-abstraction by the sp2-hybridized radical in the central ring or a 1,5-H shift followed by self-quenching could be the other possible ways to lead to the helicenes.