1422007-49-5 Usage
General Description
The chemical compound "(R)-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methylamine" is a complex organic molecule with a bicyclic structure. It consists of a bicyclo[4.2.0]octa-1,3,5-triene ring system with three methoxy groups and a methylamine functional group attached to it. (R)-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methylamine has potential applications in organic synthesis as a building block for the creation of more complex molecules. It may also have potential pharmaceutical or biological properties due to its unique structure. Further research and exploration of this compound's properties and potential applications are warranted.
Check Digit Verification of cas no
The CAS Registry Mumber 1422007-49-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,2,0,0 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1422007-49:
(9*1)+(8*4)+(7*2)+(6*2)+(5*0)+(4*0)+(3*7)+(2*4)+(1*9)=105
105 % 10 = 5
So 1422007-49-5 is a valid CAS Registry Number.
1422007-49-5Relevant articles and documents
Exploiting the Biocatalytic Toolbox for the Asymmetric Synthesis of the Heart-Rate Reducing Agent Ivabradine
Pedragosa-Moreau, Sandrine,Le Flohic, Alexandre,Thienpondt, Vivien,Lefoulon, Fran?ois,Petit, Anne-Marie,Ríos-Lombardía, Nicolás,Morís, Francisco,González-Sabín, Javier
, p. 485 - 493 (2017/02/10)
Several chemoenzymatic routes have been evaluated for the production of the heart-rate reducing agent ivabradine. Lipases and ω-transaminases have been identified as useful biocatalysts for the preparation of key enantiopure precursors. The lipase-catalysed kinetic resolution by alkoxycarbonylation of a racemic primary amine and subsequent chemical reduction of the resulting carbamate provided an N-methylated (S)-amine, one step away from ivabradine. Alternatively, the dynamic kinetic resolution by asymmetric bioamination of an aldehyde precursor enabled, in a four-step sequence, the preparative scale synthesis of enantiopure ivabradine in 50% overall yield. (Figure presented.).
