1422009-13-9Relevant academic research and scientific papers
One-pot synthesis of aromatic fused 2,3-dihydroindanone by tandem Pauson-Khand/Michael/Henry reaction
Li, Mingming,Xing, Ping,Huang, Zuogang,Jiang, Biao
, p. 49 - 54 (2013)
The intermolecular Pauson-Khand reaction between 2-ethynylbenzaldehyde and ethylene promoted by dimethyl sulfide can be utilized to synthesize 2-(2-formylphenyl)cyclopentenone efficiently. This compound and its derivatives undergo a cascade process of Michael addition reaction followed by Henry reaction with nitromethane to construct substituted aromatic fused 2,3-dihydroindanones. Furthermore, direct one-pot synthesis of aromatic fused 2,3-dihydroindanones from 2-ethynylbenzaldehyde is achieved. Copyright
