1422009-53-7Relevant academic research and scientific papers
CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
-
Paragraph 0111, (2013/03/26)
Chemical entities that are arctigenin derivatives, pharmaceutical compositions and methods of treatment of cancer are described. Treatment encompasses administration of at least one compound of Formula I, or a pharmaceutically acceptable salt thereof, to a mammalian subject, particularly a human subject, in need of such an administration and includes (i) arresting the development of clinical symptoms of the disease, such as cancer, (ii) bringing about a regression in the clinical symptoms of the disease, such as cancer, and/or (iii) prophylactic treatment for preventing the onset of the disease, such as cancer. Cancer refers to all types of cancer o neoplasm or malignant tumors found in mammals, including carcinomas and sarcomas. Examples of cancer are cancer of the brain, breast, cervix, colon, head and neck, kidney, lung, non-small cell lung, melanoma, mesothelioma, ovary, sarcoma, stomach, uterus and Medulloblastoma.
