14222-41-4

Basic information

• Product Name: S-(2-oxotetrahydrofuran-3-yl) ethanethioate
• CAS NO: 14222-41-4
• Molecular Formula: C₆H₈O₃S
• Molecular Weight: 160.1909
• Mol File: 14222-41-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 323.9°C at 760 mmHg
• Flash Point: 168.1°C
• Density: 1.28g/cm³
• Vapor Pressure: 0.000254mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: S-(2-oxotetrahydrofuran-3-yl) ethanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(2-oxotetrahydrofuran-3-yl) ethanethioate(14222-41-4)
• EPA Substance Registry System: S-(2-oxotetrahydrofuran-3-yl) ethanethioate(14222-41-4)

Safety Data

• Hazardous Substances Data: 14222-41-4(Hazardous Substances Data)

Upstream product

• 5061-21-2 α-bromo-γ-butyrolactone 
• 10387-40-3 potassium thioacetate 

Downstream Products

• 365532-17-8 1-(tert-butyloxycarbonyl)-4-{2-[(2-oxotetrahydrofuran-3-yl)sulfanyl]ethyl}piperazine 
• 14032-62-3 2-mercapto-γ-butyrolactone 

Relevant articles and documents

Visible-light induced metal-free cascade Wittig/hydroalkylation reactions

Cascade reactions are green and powerful transformations for building multiple carbon-carbon bonds in one step. Through a relay olefination and radical addition process, we were able to develop the cascade Wittig/hydroalkylation reactions induced by visible light. This metal-free radical approach features mild conditions, robustness, and excellent functionality compatibility. It allows access to saturated C3 homologation products directly from aldehydes or ketones. The synthetic utility of this method is demonstrated by a two-step synthesis ofindolizidine 209D.

ENANTIOMERS OF MERCAPTO LACTONES AND PROCESSES FOR THEIR SYNTHESIS

An improved process for the preparation of single enantiomers of formula (I), and novel intermediates and processes thereto.