1422361-75-8

Upstream product

• 151103-08-1 4-difluoromethoxy-3-hydroxybenzaldehyde 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 1422361-74-7 propyl 5-[2-(difluoromethoxy)-5-formylphenoxy]pentanoate 

Downstream Products

• 1422361-76-9 5-[5-{[(3,5-dichloropyridin-4-yl)amino]carbonyl}-2-(difluoromethoxy) phenoxy]pentanoic acid 
• 1422361-41-8 phenyl 5-[5-{[(3,5-dichloropyridin-4-yl)amino]carbonyl}-2-(difluoromethoxy)phenoxy]pentanoate 
• 1422361-72-5 C₂₄H₂₅Cl₂F₂N₃O₆S 

Relevant academic research and scientific papers

NOVEL SOFT PDE4 INHIBITORS

The present invention relates to new phosphodiesterase inhibitors, more specifically soft PDE4 inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new soft PDE4 inhibitors compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including inflammatory diseases.

NOVEL SOFT PDE4 INHIBITORS

The present invention relates to new phosphodiesterase inhibitors, more specifically soft PDE4 inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new soft PDE4 inhibitors compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including inflammatory diseases.