1422363-62-9Relevant articles and documents
A new class of NO-donor pro-drugs triggered by γ-glutamyl transpeptidase with potential for reno-selective vasodilatation
Zhang, Qingzhi,Kulczynska, Agnieszka,Webb, David J.,Megson, Ian L.,Botting, Nigel P.
, p. 1389 - 1391 (2013/02/25)
This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of γ-glutamyl transpeptidase (γ-GT), and have potential for the treatment of acute renal injury/failur