1422372-74-4Relevant academic research and scientific papers
Synthesis and cytotoxicity of new quinoline derivatives
Meshram, H. M.,Chennakesava Reddy, B.,Aravind Kumar, D.,Kalyan, M.,Ramesh, P.,Kavitha, P.,Venkateswara Rao, J.
, p. 1411 - 1416,6 (2020/08/31)
New 2,8-bis(trifluoromethyl)-4-substituted quinolines have been synthesized from 4-haloquinoline following the Suzuki protocol and N-arylation. The cytotoxicity of the synthesized compounds has been evaluated against human cancer cell lines, and among them, compounds 5a and 5g are found to be the more potent antiproliferative agents.
