14224-80-7

Upstream product

• 15210-25-0 bicyclo[10.3.0]pentadec-1⁽¹²⁾-en-13-one 
• 1501-82-2 cyclododecene 
• 24274-27-9 16-Oxa-tricyclo[10.3.1.0^1,12]hexadecan-2-one 
• 21890-07-3 16-Oxa-tricyclo[9.4.1.0^1,11]hexadecan-12-one 
• 14224-79-4 1,12-Epoxybicyclo<10.3.0>pentadecan-13-on 

Downstream Products

• 502-72-7 cyclopentadecanone 
• 34894-60-5 4-methylcyclopentadecanone 
• 14717-33-0 (Z)-cyclopentadec-4-enone 

Relevant academic research and scientific papers

Cyclopentadecanone preparation method

The invention provides a cyclopentadecanone preparation method. The method includes that cyclododecene and acryloyl chloride are subjected to reaction to obtain a ketene intermediate shown as a formula (II), the intermediate and a sulfuryl hydrazine compound are subjected to reaction to obtain a hydrazone intermediate shown as a formula (III), and the hydrazone intermediate is subjected to ring opening and hydrogenation to obtain a cyclopentadecanone product shown as a formula (V). Compared with a traditional cyclopentadecanone synthesis route, the method mainly has advantages of low cost andeasiness in acquisition of starting materials, the ketene intermediate shown as the formula (II) is obtained by high-selectivity reaction of cyclododecene and acryloyl chloride, and the integral synthesis route is simple and short in step, high in total yield and applicable to cyclopentadecanone industrial production.

An Electrochemical Variant in the Syntheses of Exaltone and Muscone: Anodic Fragmentation of α,β-Unsaturated Tosylhydrazones

Ring enlargement of bicyclopentadec-1(12)-en-13-one p-toluenesulfonylhydrazone into cyclopentadec-4-yn-1-one was accomplished under mild and controlled anodic oxidation conditions.The mechanism of this fragmentation is reconsidered.