1422430-22-5

Basic information

• Product Name: C₂₈H₃₉N₃O₄
• CAS NO: 1422430-22-5
• Molecular Weight: 481.635
• Mol File: 1422430-22-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₉N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₉N₃O₄(1422430-22-5)
• EPA Substance Registry System: C₂₈H₃₉N₃O₄(1422430-22-5)

Safety Data

• Hazardous Substances Data: 1422430-22-5(Hazardous Substances Data)

Upstream product

• 120341-33-5 1-[(tert-butoxy)-carbonyl-amino]propane-1,3-dicarboxylic acid 
• 2759-28-6 1-phenylmethylpiperazine 
• 19835-38-2 1-adamantylacetyl chloride 

Relevant articles and documents

Inhibition of Ebola virus infection: Identification of niemann-pick C1 as the target by optimization of a chemical probe

A high-throughput screen identified adamantane dipeptide 1 as an inhibitor of Ebola virus (EboV) infection. Hit-to-lead optimization to determine the structure-activity relationship (SAR) identified the more potent EboV inhibitor 2 and a photoaffinity labeling agent 3. These antiviral compounds were employed to identify the target as Niemann-Pick C1 (NPC1), a host protein that binds the EboV glycoprotein and is essential for infection. These studies establish NPC1 as a promising target for antiviral therapy.