1422433-19-9

Basic information

• Product Name: C₂₃H₂₀FN₃O₃
• CAS NO: 1422433-19-9
• Molecular Weight: 405.429
• Mol File: 1422433-19-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₀FN₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₀FN₃O₃(1422433-19-9)
• EPA Substance Registry System: C₂₃H₂₀FN₃O₃(1422433-19-9)

Safety Data

• Hazardous Substances Data: 1422433-19-9(Hazardous Substances Data)

Upstream product

• 1422432-70-9 C₁₇H₂₀FN₂O₂⁽¹⁺⁾*Br^(1-) 
• 1422432-85-6 C₂₀H₂₁FN₂O₄ 
• 1428648-06-9 C₁₆H₁₃FN₂O₄ 
• 1428648-55-8 C₁₆H₁₂ClFN₂O₃ 
• 100-61-8 N-methylaniline 
• 126921-16-2 7-fluoro-1H-indole-3-carbaldehyde 

Downstream Products

• 1422432-56-1 C₂₁H₁₆FN₃O₃ 

Relevant articles and documents

Evolution of novel tricyclic CRTh2 receptor antagonists from a (E)-2-cyano-3-(1H-indol-3-yl)acrylamide scaffold

(E)-2-(3-(3-((3-Bromophenyl)amino)-2-cyano-3-oxoprop-1-en-1-yl) -1H-indol-1-yl)acetic acid (1) was discovered in a HTS campaign for CRTh2 receptor antagonists. An SAR around this hit could be established and representatives with interesting activity profiles were obtained. Ring closing tactics to convert this hit series into a novel 2,3,4,5-tetrahydro-1H-pyrido[4, 3-b]indole based CRTh2 receptor antagonist series is presented.