1422433-34-8

Basic information

• Product Name: (±)-6-phenyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-indazol-3-ol
• Synonyms: (±)-6-phenyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-indazol-3-ol
• CAS NO: 1422433-34-8
• Molecular Weight: 378.428
• Mol File: 1422433-34-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (±)-6-phenyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-indazol-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-6-phenyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-indazol-3-ol(1422433-34-8)
• EPA Substance Registry System: (±)-6-phenyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-indazol-3-ol(1422433-34-8)

Safety Data

• Hazardous Substances Data: 1422433-34-8(Hazardous Substances Data)

Upstream product

• 127034-55-3 3,4,5-trimethoxychalcone 
• 127034-55-3 1-phenyl-3-(3,4,5-trimethoxyphenyl)-trans-prop-2-en-1-one 
• 1251828-10-0 (±)-ethyl 2-oxo-4-phenyl-6-(3,4,5-trimethoxyphenyl)cyclohex-3-encarboxylate 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 

Relevant articles and documents

Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives

Novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives were synthesized and characterized by using spectral techniques like IR, 1H NMR, 13C NMR, COSY, DEPT, and GC-MS. All these compounds were screened for anti-fungal, anti-bacterial and anti-oxidant activity. Cyclohexenone derivatives, in general, showed better anti-fungal and anti-bacterial activity than parent chalcones. Whereas, all the Indazole derivatives showed very good anti-oxidant activity and some were also found to be active as anti-bacterial agent. Among the screened compounds, 15 was found to be most active as anti-fungal agent (against Rhizoctonia solani, LC 50 = 2.36 μg mL-1), 15b was found to be most active anti-bacterial agent (against Klebsiella pneumonia, MIC = 24.68 μg mL -1) and 14b emerged as most active anti-oxidant (IC50 = 19.81 μg mL-1).