1422463-83-9Relevant academic research and scientific papers
A convenient approach for the synthesis of 2,6-diformyl- and 2,6-diacetylpyridines
Ivchenko, Pavel V.,Nifant'Ev, Ilya E.,Buslov, Ivan V.
, p. 217 - 219 (2013/02/23)
2,6-Diformyl- and 2,6-diacetylpyridines are readily accessed in good yields (60-90%) via the single-pot reaction of 2,6-pyridine dicarboxamides with LiAlH4 or MeMgCl in THF at 0-20°C. The high efficiency of the method illustrates the significance of solubility in the reduction and alkylation of difunctionalized substrates.
