14225-85-5 Usage
Benzimidazole derivative
A compound based on the benzimidazole structure 2-(2-bromo-5-chlorophenyl)-1H-benzimidazole is derived from the benzimidazole structure, which is a core structure found in many biologically active molecules.
Bromine and chlorine substituents
Presence of bromine and chlorine atoms on the phenyl ring The phenyl ring in 2-(2-bromo-5-chlorophenyl)-1H-benzimidazole has both bromine and chlorine atoms as substituents, which can influence its chemical properties and potential applications.
Potential biological activities
Anticancer and antimicrobial properties 2-(2-bromo-5-chlorophenyl)-1H-benzimidazole has been studied for its possible biological activities, including its ability to inhibit cancer cell growth and its potential as an antimicrobial agent.
Inhibitory effects on cancer cell growth
Slowing down or stopping the growth of certain types of cancer cells 2-(2-bromo-5-chlorophenyl)-1H-benzimidazole is known to exhibit inhibitory effects on the growth of certain cancer cells, making it a potential candidate for cancer treatment.
Fluorescent labeling agent
Potential use in bioimaging applications 2-(2-bromo-5-chlorophenyl)-1H-benzimidazole has been investigated for its potential as a fluorescent labeling agent, which could be useful in bioimaging applications for studying cellular processes and structures.
Versatile and potentially useful chemical
Range of potential applications in biological and chemical research 2-(2-bromo-5-chlorophenyl)-1H-benzimidazole's unique structure and properties make it a promising candidate for various applications in both biological and chemical research fields.
Check Digit Verification of cas no
The CAS Registry Mumber 14225-85-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,2 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14225-85:
(7*1)+(6*4)+(5*2)+(4*2)+(3*5)+(2*8)+(1*5)=85
85 % 10 = 5
So 14225-85-5 is a valid CAS Registry Number.
14225-85-5Relevant academic research and scientific papers
Synthesis of Trinuclear Benzimidazole-Fused Hybrid Scaffolds by Transition Metal-Free Tandem C(sp2)?N Bond Formation under Microwave Irradiation
Dao, Pham Duy Quang,Cho, Chan Sik
, p. 4088 - 4098 (2021/06/16)
2-(2-Bromoaryl)- and 2-(2-bromovinyl)benzimidazoles have been coupled and cyclized with 2-methoxy- and 2-aryloxybenzimidazoles as building blocks in the presence of a base under microwave irradiation to give a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]benzo[4,5]imidazo[1,2-c]quinazolines and -pyrimidines, respectively, in good yields. 2-(2-Bromoaryl)- and 2-(2-bromovinyl)imidazoles also reacted with 2-methoxybenzimidazoles in the presence of base under microwave irradiation to give a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]imidazo[1,2-c]quinazolines and -pyrimidines, respectively, in similar yields. This process seems to proceed via an initial C(sp2)-N coupling by an addition-elimination nucleophilic aromatic substitution (SNAr) and subsequent cyclization accompanied by extrusion of alcohols.
Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition
Xu, Shan,Lu, Juyou,Fu, Hua
supporting information; experimental part, p. 5596 - 5598 (2011/06/21)
A convenient and efficient copper-catalyzed cascade method has been developed for the synthesis of benzimidazoquinazoline derivatives via reactions of readily available substituted 2-(2-halophenyl)benzoimidazoles with amidines or guanidine under mild conditions (even at room temperature).
