1422528-60-6

Basic information

• Product Name: 4-(azidomethyl)-2-fluoro-1-methylbenzene
• CAS NO: 1422528-60-6
• Molecular Weight: 165.17
• Mol File: 1422528-60-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(azidomethyl)-2-fluoro-1-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(azidomethyl)-2-fluoro-1-methylbenzene(1422528-60-6)
• EPA Substance Registry System: 4-(azidomethyl)-2-fluoro-1-methylbenzene(1422528-60-6)

Safety Data

• Hazardous Substances Data: 1422528-60-6(Hazardous Substances Data)

Upstream product

• 145075-44-1 4-(bromomethyl)-2-fluoro-1-methylbenzene 
• 192702-79-7 (3-fluoro-4-methylphenyl)methanol 

Relevant articles and documents

Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process

A convenient synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters via a domino process is described. The synthesis employs arylmethyl azides as the precursor which undergoes an acid-promoted rearrangement to give an N-aryl iminium ion. Following the addition with ethyl 3-ethoxyacrylate, intramolecular electrophilic aromatic substitution, elimination and subsequent oxidation, the quinoline products were obtained in moderate to excellent yields.